Refer to the following important safety details for information on intended use, potential side effects and risks, considerations for specific groups, and possible drug interactions linked to the prescription treatments mentioned.
Reporting Side Effects
Riovie encourages users to promptly report any side effects or adverse reactions to a licensed healthcare provider and the pharmacy that dispensed the medication. To report suspected reactions to these medications, contact the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.
For emergencies, call 911 or go to your nearest emergency department.
Advertisements by Riovie
All advertisements from riovie.com are paid for by Riovie and are intended to market Riovie’s services. Some advertisements may feature paid actors or dramatizations. When real Riovie customers or endorsements are included, this will be clearly disclosed. Individual results may vary, and specific outcomes are not guaranteed.
Riovie’s Role
Riovie connects users with licensed healthcare providers for evaluations regarding the suitability of the treatments advertised. It may also assist with prescription coordination through an external pharmacy network.
Riovie acts as a managed services provider and does not offer medical advice, fill prescriptions, or function as a licensed healthcare facility or pharmacy. Instead, it provides technology and administrative support to enable medical consultations and prescription logistics. For further details, see Riovie’s Terms of Service.
Promotional Offers on riovie.com
Occasionally, the website may present promotional pricing or special introductory offers. Pricing may change at any time due to supply or market conditions at the discretion of riovie.com. Introductory or promotional pricing, including “first month” offers, applies only to the plan and product listed at the time of purchase.
Prescriptions and Medications
Prescription drugs require evaluation and approval by a qualified healthcare provider, and issuance is solely at the provider’s discretion. Access to treatment plans and medications is not assured.
Prescriptions issued through Riovie may be filled by licensed pharmacies within its affiliated network.
All prescription medications involve potential risks. Please review all associated safety details and consult your provider for personalized advice.
Compounded Drug Formulations
In certain situations, healthcare providers may prescribe compounded medications, which are custom-prepared by licensed compounding pharmacies based in the U.S. These medications are not FDA-approved for safety or effectiveness but may be used when alternatives are not available or appropriate.
Riovie helps facilitate compounded medication fulfillment via its partner pharmacy network. These formulations are personalized to meet individual patient requirements and may differ from commercial products.
Trademark Notice
Riovie is not affiliated with, sponsored by, or endorsed by the manufacturer of any brand-name medication. Any brand names referenced are the property of their respective owners and are used for identification only.
Contact Information
For any questions about Riovie’s services or advertising content, please reach out to support@riovie.com.
Sermorelin — Subcutaneous Injection
Important Safety Information Regarding Compounded Sermorelin
Please be aware that compounded drugs are not FDA-approved and do not undergo clinical studies to evaluate for safety and efficacy. Your healthcare provider may prescribe compounded sermorelin based on your medical consultation.
Sermorelin is a growth hormone-releasing hormone (GHRH) analog. It does not supply growth hormone directly; it signals the pituitary gland to release more of the body’s own growth hormone, so output remains subject to normal feedback regulation. It is prescribed at a provider’s discretion as part of a broader wellness plan and is not a treatment for obesity, and it is not a substitute for diagnosing or treating growth hormone deficiency.
Do not use sermorelin if:
- You are pregnant, trying to become pregnant, or breastfeeding.
- You have an active or suspected malignancy.
- You have had a serious allergic reaction to sermorelin or to any component of the formulation.
Inform your healthcare provider if you:
- Have a history of cancer of any kind.
- Have diabetes, prediabetes, or impaired glucose tolerance.
- Have untreated or poorly controlled hypothyroidism, or any pituitary, adrenal, or other endocrine disorder — these can blunt or alter the response.
- Take glucocorticoids, thyroid medication, or any other prescription medication or supplement.
- Are acutely or critically ill.
Serious risks include:
- Serious allergic reactions, including reactions at the injection site
- Changes in blood glucose and insulin sensitivity
- Theoretical potential to promote the growth of an existing malignancy
- Effects on thyroid or adrenal function
- Fluid retention, joint pain, or carpal tunnel-type symptoms
Common side effects: pain, redness, swelling, or itching at the injection site, headache, flushing, dizziness, drowsiness, hyperactivity or restlessness, difficulty swallowing, nausea, vomiting, pallor, and changes in sleep or appetite.
Administration: Inject subcutaneously once daily at bedtime on an empty stomach, rotating sites in the stomach, thigh, or upper arm, unless your clinician instructs otherwise. Do not eat for a period before and after your dose if your clinician directs you to fast around dosing.
Monitoring: Your provider may order periodic laboratory work, which can include IGF-1 and blood glucose, before or during treatment.
Reporting side effects: Contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Sermorelin — Sublingual Troche
Important Safety Information Regarding Compounded Sermorelin Troches
Compounded sermorelin troches are not FDA-approved but may be prescribed legally based on your provider’s assessment. The troche delivers the same compounded active ingredient as the injection by a different route; the amount absorbed can differ between routes and between individuals.
All of the contraindications, precautions and serious risks listed for sermorelin injection above apply equally to the troche. Review that section in full before starting.
Inform your healthcare provider if you also:
- Have mouth sores, gum disease, or any condition affecting the lining of your mouth or throat.
- Have had an allergic reaction to a flavoring, sweetener, or troche base.
- Have difficulty holding a troche in place until it dissolves.
Common side effects: headache, flushing, dizziness, drowsiness, restlessness, nausea, and changes in sleep or appetite, plus route-specific effects — irritation, numbness, tingling, dryness, or an altered or lingering taste where the troche dissolves. Sublingual delivery avoids injection-site reactions entirely, but oral or throat irritation is more likely.
Administration: Place the troche completely under your tongue once daily at bedtime on an empty stomach and let it dissolve fully without chewing or swallowing it whole. Avoid eating or drinking until it has dissolved, unless your clinician instructs otherwise.
Monitoring: Your provider may order periodic laboratory work, which can include IGF-1 and blood glucose, before or during treatment.
Reporting side effects: Contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
