MOTS-C injections onlineCellular energy. Metabolic support.
MOTS-C is a peptide your mitochondria make naturally, studied for cellular energy, metabolic signaling and exercise adaptation. Steady support, not a stimulant — clinician-guided care, made simple.
- From $160/mo, no membership or hidden fees
- A peptide your own mitochondria make, studied for energy and metabolism
- Single-ingredient MOTS-C from a licensed U.S. pharmacy
- No insurance needed, shipped to your door if prescribed
| Option | 1 Month | 3 Month | Per month |
|---|---|---|---|
| Injection | $175 | $479 | $160 |
What you get with Riovie
- Single-ingredient MOTS-C injection, with dose adjustments if clinically appropriate
- Quick online assessment and licensed clinician review
- Secure portal messaging and scheduled check-ins with your clinician
- Secure portal messaging with Riovie Support
- If prescribed, medication ships directly to your door — no pharmacy trip required
- All plans include supplies, shipping, and ongoing clinical monitoring
What to expect
Steady, not a stimulant. MOTS-C is positioned around mitochondrial and metabolic support, not a jolt of energy you feel right after a dose.
Any noticeable changes would be expected to develop gradually. Human research is still early, so your clinician sets expectations for your situation.
How to take it
- Injection: a small subcutaneous (under-the-skin) shot on the schedule your clinician sets, rotating sites each time.
- Many people pair dosing with their training days — your clinician will tell you what fits your plan.
- Your clinician sets your starting dose and how long you take it, and adjusts over time if clinically appropriate.
Active, and want to stay that way?
Your body already makes MOTS-C. Levels rise when you exercise, and research suggests they tend to fall with age.
For active adults in their 40s, 50s and beyond, MOTS-C is a peptide studied for how it may support cellular energy, metabolic health and workout capacity.
Your clinician builds your plan around your routine and your health history.
Potential side effects
Human safety data on MOTS-C are limited. Reported side effects may include pain, redness, swelling or itching where you inject, headache, tiredness, flushing, and a faster heartbeat. Because MOTS-C is studied for effects on blood sugar, tell your clinician if you take diabetes medication. Tell your clinician about anything that persists or worsens.
Prescription required; treatment is subject to your provider’s evaluation and approval. Taxes may apply where required. Product imagery is stylized for marketing and does not reflect actual labeling, strength or size. Compounded products are not approved, nor evaluated for safety, efficacy, or quality, by the FDA. See Important Safety Information for full pricing and promotional terms.
The science, simply
MOTS-C is a peptide coded in your mitochondrial DNA. It acts as a messenger between your mitochondria and the rest of the cell. Studies show:
- Exercise turns it up — nearly 12× higher in muscle after a bike workout in adults
- Physical capacity — older mice treated late in life roughly doubled treadmill running
- Metabolic health — improved insulin sensitivity in mice on a high-fat diet
- Cellular energy — activates AMPK, a key cellular energy sensor
Most research so far is in lab and animal studies. Results vary. Your clinician helps you track yours.
Sources: Reynolds 2021 · Lee 2015
The science, simply provides and inspires your access to research for yourself, this is not at all medical advice nor does it imply offerings or expectations of results or treatments from Riovie Operations LLC.
Why Riovie?
Provider Review
Licensed provider eligibility review
Medication Support
Included if clinically appropriate
Ongoing Support
Message your clinician or Riovie Support as needed