Riovie compounded GLP-1 injection vial with syringe

Stylized vial for marketing purposes only; image does not reflect the actual label or size of prescription vial. Compounded products are not approved nor evaluated for safety, efficacy, or quality by the FDA.

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LegitScript certifiedPrescribed by licensed physicians. Shipped from licensed U.S. pharmacies.

Compounded GLP-1 injections

A once-per-week GLP-1 weight loss injection.

Unlimited 24/7 support
No hidden fees
No insurance required
Same price, every dose
Plan Tirzepatide Semaglutide
Introductory (Billing Plan) $139 $99
1 Month $199 $149
3 Month $189 / month $113 / month

Three formulations. One transparent price.

Standard GLP-1 GLP-1 + B12 GLP-1 + Glycine

All available at the same listed price, with no added formulation fee.

Your licensed provider will determine the appropriate medication and formulation based on your health history, clinical eligibility, and availability.

Prescription required; treatment is subject to your provider’s evaluation and approval. Taxes may apply where required. See Important Safety Information for full pricing and promotional terms.

Get Started
What you get with Riovie
  • Multiple treatment plan options with dose adjustments if clinically appropriate
  • Quick online assessment and licensed physician review
  • Secure 24/7 messaging and scheduled check-ins with your physician
  • Secure 24/7 messaging with Riovie Support
  • If prescribed, medication ships directly to your door — no pharmacy trip required
  • All plans include supplies, shipping, and ongoing clinical monitoring
  • All plans include Riovie digital GLP Metabolic Success Guide
How to take it
  • Once-weekly subcutaneous injection, on the same day each week (unless instructed otherwise by your physician).
  • Step-by-step dose-escalation schedule to support tolerance and minimize side effects
Potential side effects

Common side effects of GLP-1 injections may include nausea, diarrhea, and vomiting. To help your body adjust, eligible patients may add-on a fast-acting anti-nausea medication.

Premium value, made simple

Premium formulation. Same low price.

Elsewhere, B12 or glycine combinations can carry premium pricing. Riovie keeps eligible premium and base GLP-1 formulations at the same low plan price.*

Choose your GLP-1 formulation: standard GLP-1, GLP-1 plus B12, or GLP-1 plus glycine — all the same price, no premium upcharge.
Semaglutide$99introductory billing plan
Tirzepatide$139introductory billing plan

Base GLP-1 is also available: semaglutide and tirzepatide at these same plan prices.

Start at Riovie’s low price

*Introductory billing plan prices shown. If clinically appropriate, selected, and prescribed, available formulations may include base semaglutide or tirzepatide, or either medication compounded with B12 or glycine. Base or premium formulation choice does not change the plan price. Competitor pricing and formulations vary. Vial imagery is stylized and does not reflect the actual label or vial size. Compounded drugs are not FDA-approved or evaluated for safety, effectiveness, or quality.

Why Riovie?

Provider Review

Licensed provider eligibility review

Medication Support

Included if clinically appropriate

26-Page GLP Digital Guide

Nutrition, movement, and side-effect support

How It Works

Online Visit
Provider Review
Start With Support
Start Your Online Visit

From the Riovie Library

The concept is here. The plan is in the guide.

The complete Riovie Metabolic Success Digital Guide turns these pillars into a plan you can follow — the Riovie Plate, the hand-portion guide, protein targets, the daily 3×5-minute practices, a full Day in the Life, kitchen-stocking lists, and strategies for common GLP-1 challenges. It’s part of the wrapped care included when you begin treatment with a Riovie provider.

Prefer a taste first? Get a free preview of the digital guide.

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Common questions

What are the Premium versions I heard about?
If clinically appropriate and prescribed, your provider may select base semaglutide or tirzepatide, or a formulation compounded with B12 or glycine. Riovie offers eligible base and premium formulations at the same plan price; prescriptions are never guaranteed.
Do I still need to eat well on a GLP-1?
Yes. The medication reduces hunger, but eating less isn’t the same as getting enough. Your body still needs protein and nutrients to protect muscle, support metabolism, and keep your energy, skin, and hair thriving. Less hunger isn’t permission to stop nourishing your body.
Will I lose muscle on a GLP-1?
Eating less can lead to losing muscle alongside fat. Prioritizing protein at each meal and including regular strength training helps protect lean mass — the guide gives specific protein targets and a simple strength approach.
What helps with common GLP-1 side effects?
Staying hydrated, eating small nutrient-dense meals, supporting electrolytes, gentle daily movement, and prioritizing sleep are common starting points for things like nausea, bloating, and fatigue. Most side effects ease with time and the right strategies — and your care team can help adjust. The guide includes a fuller challenge-by-challenge breakdown.
How much protein should I aim for?
A simple starting point is a palm-sized portion of protein at every meal. The guide gives specific per-meal targets you can tailor to your goals and activity level.
Is intense exercise required?
No. Consistency beats intensity. A 10-minute walk after meals and two to three strength sessions a week do more over time than occasional hard workouts.
Is this medical advice?
No. This is educational content, not medical advice. GLP-1 medications are prescription products — always follow the recommendations of your licensed healthcare provider, which is exactly what the Riovie care team provides.

Consult a licensed provider. Prescription required. Not for everyone.