Women’s Sexual Health

PT-141 for women

A compounded peptide prescribed for women, taken ahead of intimacy — not on a daily schedule.

Message support in the Riovie Portal
No hidden fees
No insurance required
Use only when you need it
Option 1 Month 3 Month Per month
Injection $159 $405 $135
Nasal Spray $99 n/a — 1-month plan only n/a — 1-month plan only
What you get with Riovie
  • A women’s sexual health plan with dose adjustments if clinically appropriate
  • Quick online assessment and licensed clinician review
  • Secure portal messaging and scheduled check-ins with your clinician
  • Secure portal messaging with Riovie Support
  • If prescribed, medication ships directly to your door — no pharmacy trip required
  • All plans include supplies, shipping, and ongoing clinical monitoring
How to take it
  • Inject subcutaneously in the abdomen or thigh about 45 minutes before anticipated intimacy — this is taken as needed, not on a daily schedule.
  • No more than one dose in any 24-hour period, and no more than eight doses in a month. Use aseptic technique and rotate sites between doses.
  • Your clinician sets your dose and adjusts it over time if clinically appropriate. Do not increase your dose or use it more often on your own.
Want to want to?

Low libido is common, and it’s not a willpower problem. PT-141 works on desire pathways in the brain, not blood flow — which is why it was studied in women with low desire.

No daily pill, no schedule. Take it about 45 minutes ahead, only when you choose.

Stress, kids, a busy season or midlife changes — tell your clinician what’s shifted with your sex drive, and your plan is built around you.

Potential side effects

Nausea is the most commonly reported side effect and is usually strongest with the first dose. Flushing, headache, vomiting, and pain, redness or swelling where you inject are also common. PT-141 raises blood pressure and lowers heart rate for a few hours after each dose, so it is not appropriate for everyone. Using it more often than directed can cause darkening of the skin, gums, or face that may not fully fade. Tell your clinician about anything that persists or worsens.

The science, simply

PT-141 works on desire pathways in the brain, not on blood flow. You take it only when you choose. Studies show it may support:

  • More desire — rose more than placebo in two 24-week trials of 1,267 women
  • Less distress — less bother about low desire than placebo
  • Arousal — in men, erections began about 30 minutes after a nasal dose
  • Results that last — desire gains held through a year of use

Results vary. Your clinician helps you track yours.

Sources: Kingsberg 2019 · FDA trial summary · Diamond 2004 · Simon 2019

The science, simply provides and inspires your access to research for yourself, this is not at all medical advice nor does it imply offerings or expectations of results or treatments from Riovie Operations LLC.

Why Riovie?

Provider Review

Licensed provider eligibility review

Medication Support

Included if clinically appropriate

Discreet Delivery

Ships directly to your door — no pharmacy trip

How It Works

Online Visit
Provider Review
Start With Support
Choose Your Option

Common questions

What is PT-141?
PT-141 (bremelanotide) is a melanocortin receptor agonist prescribed through Riovie for women. Unlike medications that work on blood flow, it acts on pathways in the brain involved in sexual desire and arousal. It’s taken ahead of anticipated intimacy rather than on a daily schedule.
What can PT-141 help with?
It may support desire and ease the distress that comes with a low sex drive — by working on desire pathways in the brain, not blood flow.
How is PT-141 different from ED pills like sildenafil?
ED pills like sildenafil increase blood flow. PT-141 works in the brain, on desire itself — which is why it has been studied in women with low desire.
Injection or nasal spray — which one should I choose?
Both use the same compounded active ingredient. The injection is the form studied in the large women’s trials; the nasal spray suits people who would rather not inject. The amount absorbed can differ between forms. Your clinician will discuss which fits you.
When do I take it?
Roughly 45 minutes before anticipated sexual activity, as a subcutaneous injection in the abdomen or thigh. Your clinician will confirm timing for you. It’s used as needed — there’s no daily dose to remember.
How often can I use it?
No more than one dose in any 24-hour period, and no more than eight doses in a month. Using it more often than that raises the risk of side effects, including darkening of the skin and gums that may not fully fade.
Will it make me nauseated?
Nausea is the most commonly reported side effect and is usually strongest with the first dose, easing with later ones. Your clinician can discuss timing, dose, and whether an anti-nausea option is appropriate for you.
Who should not take PT-141?
PT-141 raises blood pressure and lowers heart rate for a few hours after each dose, so it isn’t appropriate for people with uncontrolled high blood pressure or known cardiovascular disease. Tell your provider about your blood pressure, your heart history, and every medication you take — oral naltrexone in particular, which PT-141 can interfere with.
Do I need insurance?
No. Riovie does not bill insurance. The price you’re presented is the price you pay, plus applicable taxes where required. HSA or FSA eligibility can apply to some program components — we recommend checking with your plan administrator before purchase.
Is PT-141 FDA-approved?
Bremelanotide, the active ingredient, is FDA-approved as a brand-name autoinjector for low sexual desire in premenopausal women. Riovie’s PT-141 is prepared by a licensed compounding pharmacy with a prescription. Compounded medicines are not FDA-approved.
Is this medical advice?
No. This is educational content, not medical advice. PT-141 is a prescription product — always follow the recommendations of your licensed healthcare provider, which is exactly what the Riovie care team provides.

Consult a licensed provider. Prescription required. Not for everyone.